原著論文受賞

詳しい業績はこちら(PDF)

論文

2020

  1. Ayumi Yamamoto, Takashi Tsukamoto, Kenshiro Suzuki, Eri Hashimoto, Yoshihiro Kobashigawa, Kousuke Shibasaki, Takeshi Uchida, Fuyuhiko Inagaki, Makoto Demura, Koichiro Ishimori.
    Spectroscopic Characterization of Halorhodopsin Reconstituted into Nanodisks Using Native Lipids
    Biophys. J. 118, 1-18 (2020). [Link]
  2. Satoshi Yasuda, Tomoki Akiyama, Sayaka Nemoto, Tomohiko Hayashi, Tetsuya Ueta, Keiichi Kojima, Takashi TsukamotoSatoru Nagatoishi, Kouhei Tsumoto, Yuki Sudo, Masahiro Kinoshita, Takeshi Murata.
    Methodology for Further Thermostabilization of an Intrinsically Thermostable Membrane Protein Using Amino Acid Mutations with Its Original Function Being Retained
    J. Chem. Inf. and Model. 60 (3), 1709-1716 (2020). [Link]

2019

  1. Azusa Iizuka, Kousuke Kajimoto, Tomotsumi Fujisawa, Takashi Tsukamoto, Tomoyasu Aizawa, Naoki Kamo, Kwang-Hwan Jung, Masashi Unno, Makoto Demura, Takashi Kikukawa.
    Functional importance of the oligomer formation of the cyanobacterial H+pump Gloeobacter rhodopsin
    Sci. Rep. 9, 10711 (2019). [Link]
  2. Taro Yamanashi, Misayo Maki, Keiichi Kojima, Atsushi Shibukawa, Takashi Tsukamoto,Srikanta Chowdhury, Akihiro Yamanaka, Shin Takagi, Yuki Sudo.
    Quantification of the neural silencing activity of anion channelrhodopsin in Caenorhabditis elegansand their applicability for long-term illumination
    Sci. Rep. 9, 7863 (2019). [Link]

2018

  1. Takashi Tsukamoto*, Chihiro Kikuchi, Hiromu Suzuki, Tomoyasu Aizawa, Takashi Kikukawa, Makoto Demura.
    “Implications for the impairment of the rapid channel closing of Proteomonas sulcata anion channelrhodopsin 1 at high Cl concentrations”
    Sci. Rep. 8, 13445 (2018). [Link] *Corresponding author
  2. Tomomi Shionoya, Misao Mizuno, Takashi Tsukamoto, Kento Ikeda, Hayato Seki, Keiichi Kojima, Mikihiro Shibata, Izuru Kawamura, Yuki Sudo, Yasuhisa Mizutani.
    “High Thermal Stability of Oligomeric Assemblies of Thermophilic Rhodopsin in a Lipid Environment”
    J. Phys. Chem. B 122 (27), 6945-6953 (2018). [Link]
  3. Riho Takayama, Akimasa Kaneko, Takashi Okitsu, Satoshi P. Tsunoda, Kazumi Shimono, Misao Mizuno, Keiichi Kojima, Takashi Tsukamoto, Hideki Kandori, Yasuhisa Mizutani, Akimori Wada, Yuki Sudo.
    “Production of a Light-Gated Proton Channel by Replacing the Retinal Chromophore with Its Synthetic Vinylene Derivative”
    J. Phys. Chem. Lett. 9 (11), 2857-2862 (2018). [Link]
  4. Yu Nakajima, Takashi Tsukamoto, Yohei Kumagai, Yoshitoshi Ogura, Tetsuya Hayashi, Jaeho Song, Takashi Kikukawa, Makoto Demura, Kazuhiro Kogure, Yuki Sudo, Susumu Yoshizawa. Akimori Wada, Yuki Sudo.
    “Presence of a Haloarchaeal Halorhodopsin-Like Cl Pump in Marine Bacteria”
    Microbes Environ. 33 (1), 89-97 (2018). [Link]
  5. Saki Inoue, Susumu Yoshizawa, Yu Nakajima, Keiichi Kojima, Takashi Tsukamoto, Takashi Kikukawa, Yuki Sudo.
    “Spectroscopic Characteristics of Rubricoccus marinus Xenorhodopsin (RmXeR) and a Putative Model for its Inward H+ Transport mechanism”
    Phys. Chem. Chem. Phys. 20 (5), 3172-3183 (2018). [Link]

2017

  1. Naoya Honda, Takashi Tsukamoto, Yuki Sudo.
    “Comparative Evaluation of the Stability of Seven-Transmembrane Microbial Rhodopsins to Various Physicochemical Stimuli”
    Chem. Phys. Lett. 682, 6-14 (2017). [Link]
  2. Akiko Niho†, Susumu Yoshizawa†, Takashi Tsukamoto†, Marie Kurihara, Shinya Tahara, Yu Nakajima, Misao Mizuno, Hikaru Kuramochi, Tahei Tahara, Yasuhisa Mizutani, Yuki Sudo.
    “Demonstration of a Light-Driven SO42- Transporter and Its Spectroscopic Characteristics”
    J. Am. Chem. Soc. 139 (12), 4376-4389 (2017). [Link] †Equal contribution.
  3. Kanae Kanehara, Susumu Yoshizawa, Takashi Tsukamoto, Yuki Sudo.
    “A Phylogenetically Distinctive and Extremely Heat Stable Light-Driven Proton Pump from the Eubacterium Rubrobacter xylanophilus DSM 9941T
    Sci. Rep. 7, 44427 (2017). [Link]
  4. Takashi Tsukamoto*, Susumu Yoshizawa, Takashi Kikukawa, Makoto Demura, Yuki Sudo. “Implications for the Light-Driven Chloride Ion Transport Mechanism of Nonlabens marinus Rhodopsin 3 by Its Photochemical Characteristics”
    J. Phys. Chem. B 121 (9), 2027-2038 (2017). [Link] *Corresponding author.
  5. Satoko Doi, Takashi Tsukamoto, Susumu Yoshizawa, Yuki Sudo.
    “An Inhibitory role of Arg-84 in Anion Channelrhodopsin-2 Expressed in Escherichia coli”
    Sci. Rep.
    7, 41879 (2017). [Link]

2016

  1. Akihiko Sakamoto, Takashi Tsukamoto, Yuji Furutani, Yuki Sudo, Kazuyuki Shimada, Akihiro Tomita, Hitoshi Kiyoi, Takashi Kato, Takashi Funatsu.
    “Live-Cell Single-Molecule Imaging of the Cytokine Receptor MPL for Analysis of Dynamic Dimerization”
    J. Mol. Cell Biol. 8 (6), 553-555 (2016). [Link]
  2. Takashi Tsukamoto, Kenji Mizutani, Taisuke Hasegawa, Megumi Takahashi, Naoya Honda, Naoki Hashimoto, Kazumi Shimono, Keitaro Yamashita, Masaki Yamamoto, Seiji Miyauchi, Shin Takagi, Shigehiko Hayashi, Takeshi Murata, Yuki Sudo.
    “X-ray Crystallographic Structure of Thermophilic Rhodopsin: Implications for High Thermal Stability and Optogenetic Function”
    J. Biol. Chem. 291 (23), 12223-12232 (2016). [Link]

2015

  1. Satoko Doi, Arisa Mori, Takashi Tsukamoto, Louisa Reissig, Kunio Ihara, Yuki Sudo.
    “Structural and Functional Roles of the N- and C-terminal Extended Modules in Channelrhodopsin-1”
    Photochem. Photobiol. Sci. 14 (9), 1628-1636 (2015). [Link]
  2. Takashi Kikukawa, Chikara Kusakabe, Asami Kokubo, Takashi Tsukamoto, Masakatsu Kamiya, Tomoyasu Aizawa, Kunio Ihara, Naoki Kamo, Makoto Demura.
    “Probing the Cl-pumping Photocycle of pharaonis Halorhodopsin: Examinations with Bacterioruberin, an Intrinsic Dye, and Membrane Potential-Induced Modulation of the Photocycle”
    Biochim. Biophys. Acta 1847 (8), 748-758 (2015). [Link]
  3. Keiichi Inoue, Takashi Tsukamoto, Kazumi Shimono, Yuto Suzuki, Seiji Miyauchi, Shigehiko Hayashi, Hideki Kandori, Yuki Sudo.
    “Converting a Light-Driven Proton Pump into a Light-Gated Proton Channel”
    J. Am. Chem. Soc. 137 (9), 3291-3299 (2015). [Link]
  4. 塚本卓, 須藤雄気.
    “好熱性細菌のレチナールタンパク質”
    生物物理 55 (2), 092-094 (2015). [Link]

2014

  1. Takashi Tsukamoto, Makoto Demura, Yuki Sudo.
    “Irreversible Trimer to Monomer Transition of Thermophilic Rhodopsin upon Thermal Stimulation”
    J. Phys. Chem. B 118 (43), 12383-12394 (2014). [Link]
  2. Keiichi Inoue, Takashi Tsukamoto, Yuki Sudo.
    “Molecular and Evolutionary Aspects of Microbial Sensory Rhodopsins”
    Biochim. Biophys. Acta 1837 (5), 562-577 (2014). [Link]
  3. Takashi Tsukamoto, Yuki Sudo.
    “Sensory rhodopsins” eLS (Microbiology) (2014).
    DOI: 10.1002/9780470015902.a0022838
  4. 水谷健二, 橋本直記, 塚本卓, 須藤雄気, 村田武士.
    “微生物型ロドプシンTRのX線結晶構造解析”
    Photon Factory Activity Report 2013 #31 (2014). [Link]

2013

  1. Takashi Tsukamoto*, Xianglan Li, Hiromi Morita, Takashi Minowa, Tomoyasu Aizawa, Nobutaka Hanagata, Makoto Demura.
    “Role of S-palmitoylation on IFITM5 for the Interaction with FKBP11 in Osteoblast Cells”
    PLOS ONE 8 (9), e75831 (2013). [Link] *Corresponding author.
  2. Takashi Tsukamoto, Keiichi Inoue, Hideki Kandori, Yuki Sudo.
    “Thermal and Spectroscopic Characterization of a Proton Pumping Rhodopsin from an Extreme Thermophile”
    J. Biol. Chem. 288 (30), 21581-21592 (2013). [Link] Faculty of 1000 “Recommended”.
  3. Takashi Tsukamoto, Takashi Kikukawa, Takuro Kurata, Kwang-Hwan Jung, Naoki Kamo, Makoto Demura.
    “Salt Bridge in the Conserved His-Asp Cluster in Gloeobacter Rhodopsin Contributes to Trimer Formation” FEBS Lett. 587 (4), 322-327 (2013). [Link]

2012

  1. Takashi Tsukamoto, Takanori Sasaki, Kazuhiro J. Fujimoto, Takashi Kikukawa, Masakatsu Kamiya, Tomoyasu Aizawa, Keiichi Kawano, Naoki Kamo, Makoto Demura.
    “Homotrimer Formation and Dissociation of pharaonis Halorhodopsin in Detergent System”
    Biophys. J. 102 (12), 2906-15 (2012). [Link]

2011

  1. Yasutaka Yamashita, Takashi Kikukawa, Takashi Tsukamoto, Masakatsu Kamiya, Tomoyasu Aizawa, Keiichi Kawano, Seiji Miyauchi, Naoki Kamo, Makoto Demura.
    “Expression of salinarum Halorhodopsin in Escherichia coli Cells: Solubilization in the Presence of Retinal Yields the Natural State”
    Biochim. Biophys. Acta 1808 (12), 2905-12 (2011). [Link]

受賞

  • 2005年10月  北海道大学 新渡戸賞
  • 2010年9月  国立研究開発法人 物質・材料研究機構 Award of NIMS Internship Program 2010